Guadalupe Fernández Valencia "La Patrona" moved both drugs and money for the Sinaloa Cartel.
A tip about a stolen van led to their arrest.
Authorities apprehended Couch and his mother, Tonya Couch, last month in Puerto Vallarta, Mexico.
A Spanish court has ruled that a prominent former Mexican politician who was arrested on a Spanish warrant should be held in custody while officers investigate alleged corruption.
An important aspect which helped locate him was discovering Guzmán's intention to have a biographical film made. He contacted actresses and producers, which was part of one line of investigation.
Prosecutors say the crimes were related to sex and drugs, and the characteristics could link Andrés Ulises Castillo Villarreal to 12 other killings.
Mark Salling was taken into custody Tuesday after a warrant was served at his home.
Ethan Couch and his mother, Tonya Couch stayed first at a resort known as Los Tules, near the beach.
After a rough childhood that included a period of homelessness in high school Lakeisha Holloway had become an award-winning high school graduate and caring mother.
CBP officers discovered 12 packages of suspected narcotics worth US$256,000 in a BMW SUV that arrived from Mexico.